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Menopause Profile is a noninvasive salivary/urine assessment that measures levels of progesterone, oestradiol, testosterone in addition to markers of bone turnover and oestrogen metabolism.

Results can be used to identify imbalances contributing to menopausal symptoms as well as various systemic disorders. Once the identification of hormonal imbalances has been established, it is advisable to seek the services of a professional Nutritionist who can customise a treatment plan for you. Combined with information about bone turnover and oestrogen-dependent conditions, this profile provides a valuable assessment of menopausal related conditions.

Following menopause, a marked decrease in oestrogen production can result in distinct changes in female physiology. Dramatic reductions in hormone levels or imbalances between oestrogen, progesterone and testosterone can lead to:

• Hot flushes • Impaired memory
• Vaginitis • Altered lipid metabolism
• Dyspareunia • Accelerated ageing of skin

By the time a woman reaches menopause, her total oestrogen production has typically declined by 70-80% and her androgen production by 50%. Reduced hormonal levels are associated with increased risk for osteoporosis and cardiovascular disease. In addition, potential functional impairments include:

• Immune regulation • Sex drive
• Mood control • Cognition
• Glycemic control

Establishing baseline measurements of oestrogens, progesterone and testosterone is critical in determining the need for hormone replacement therapy (HRT). Hormone levels may be normal, indicating that HRT is not needed. Reference ranges are provided for both non-supplementing and supplementing pre and post-menopausal women. Excess levels of oestradiol or testosterone may signify a higher risk of breast or endometrial cancer.

Procedure:
Menopause Profile examines a single saliva sample for levels of oestradiol, progsterone and testosterone. Measurements for markers of bone turnover as an assessment of osteoporosis risk and for oestrogen metabolsism as an assessment for cancer risk are made from a single first morning urine. Research has established salivary hormone assessment to be reliable and clinically useful. Salivary assessment offers the distinct advantage of detecting the free, bioavailable fraction of steroid hormones.